PGT-M conditions
The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.
When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.
If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.
Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.
Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.
| Condition name | Status | OMIM number | Documents |
|---|---|---|---|
| Coenzyme Q10 Deficiency, Primary, 4 (COQ10D4) | approved | 612016 | |
| Coenzyme Q10 Deficiency, Primary, 5 (COQ10D5) | awaiting consideration | 614654 | |
| Coffin-Lowry Syndrome (CLS) | approved | 303600 | |
| Cohen Syndrome (COH1) | approved | 216550 | |
| Cohen-Gibson Syndrome (COGIS), OMIM #617561 | approved | 617561 | |
| Combined Immunodeficiency, X-linked (CIDX) | approved | 312863 | |
| Combined Oxidative Phosphorylation Deficiency 1 (COXPD1) | approved | 609060 | |
| Combined Oxidative Phosphorylation Deficiency 10 (COXPD10) | approved | 614702 | |
| Combined Oxidative Phosphorylation Deficiency 11 (COXPD11) | approved | 614922 | |
| Combined Oxidative Phosphorylation Deficiency 12 (COXPD12) | approved | 614924 | |
| Combined Oxidative Phosphorylation Deficiency 13 (COXPD13) | approved | 614932 | |
| Combined Oxidative Phosphorylation Deficiency 14 (COXPD14) | approved | 614946 | |
| Combined Oxidative Phosphorylation Deficiency 15 (COXPD15) | approved | 614947 | |
| Combined Oxidative Phosphorylation Deficiency 16 (COXPD16) | approved | 615395 | |
| Combined Oxidative Phosphorylation Deficiency 17 (COXPD17) | approved | 615440 | |
| Combined Oxidative Phosphorylation Deficiency 18 (COXPD18) | approved | 615578 | |
| Combined Oxidative Phosphorylation Deficiency 19 (COXPD19) | approved | 615595 | |
| Combined Oxidative Phosphorylation Deficiency 2 (COXPD2) | approved | 610498 | |
| Combined Oxidative Phosphorylation Deficiency 20 (COXPD20) | approved | 615917 | |
| Combined Oxidative Phosphorylation Deficiency 21 (COXPD21) | approved | 615918 | |
