Epilepsy, Familial Focal, with Variable Foci 3 (FFEVF3)

Epilepsy, Familial Focal, with Variable Foci 3 (FFEVF3)

OMIM number: 617118

Comments closing date: 29/02/2024

Autosomal dominant nocturnal frontal lobe
epilepsy (ADNFLE) is an uncommon, inherited
form of epilepsy. People with ADNFLE have
seizures that usually occur at night during sleep.
Some people with ADNFLE also have seizures
during the day. These seizures can last from a few
seconds to a few minutes, and can vary from
causing simple arousal from sleep, to dramatic
muscle spasms and movements. Episodes tend to
become milder and less frequent with age. It is
diagnosed based on symptoms and the results of
tests such as an EEG. ADNFLE is inherited in an
autosomal dominant manner and in this patient is
caused by a genetic change in NPRL3 gene.
Seizures can usually be controlled with anti seizure
medications.

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