PGT-M conditions
The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.
When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.
If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.
Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.
Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.
Condition name | Status | OMIM number | Documents |
---|---|---|---|
Congenital hereditary cataract, type 23 (CTRCT23) | approved | 610425 | |
Congenital hereditary cataract, type 30 (CTRCT30) | approved | 116300 | |
Congenital hereditary cataract, type 33 (CTRCT33) | approved | 611391 | |
Congenital hereditary cataract, type 34 (CTRCT34) | approved | 612968 | |
Congenital hereditary cataract, type 38 (CTRCT38) | approved | 614691 | |
Congenital hereditary cataract, type 39 (CTRCT39) | approved | 615188 | |
Congenital hereditary cataract, type 40 (CTRCT40) | approved | 302200 | |
Congenital hereditary cataract, type 44 (CTRCT44) | approved | 616509 | |
Congenital hereditary cataract, type 6 (CTRCT6) | approved | 116600 | |
Congenital hereditary cataract, type 9 (CTRCT9) | approved | 604219 | |
Congenital hypomyelinating neuropathy 1 | approved | 605253 | |
Congenital hypomyelinating neuropathy 2 | approved | 618184 | |
Congenital hypomyelinating neuropathy 3 (CHN3) | approved | 618186 | |
Congenital Mitochondrial Encephalomyopathy | approved | 500002 | |
Congenital Myopathy 16 (CMYP16) | awaiting consideration | 618524 | |
Congenital stationary night blindness Type 1A (CSNB1A) | approved | 310500 | |
Conradi-Hunermann-Happle Syndrome | approved | 302960 | |
Convulsions, Familial Infantile, with Paroxysmal Choreoathetosis, | approved | 602066 | |
Corpus Callosum, Agenesis of, with Abnormal Genitalia | approved | 300004 | |
Cowden syndrome (CS)/PTEN Hamartoma Tumour Syndrome (PHTS) | approved | 601728, 158350, 153480, 605309 | |